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NEJM 2025 (REDEFINE-1) Davies MJ, et al

10.1038/nn.2741 100 RasmussenT

This anti-apoptotic activity in lymphoid tissue contributes to preservation of immune system capacity during aging and environmental challenges

Quick takeaway: Researchers have not established BPC-157 as a reliable, direct weight-loss tool in humans

LL-37's diverse roles in immunity and host defense warrant further research to unravel its precise mechanisms of action and potential applications in clinical medicine

In the following part, we will describe the different vaccine-based strategies of senotherapeutics that have been studied, and we will show the limitations of some of them to be used into clinics