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The Result Dozens of peptides sit in a regulatory limbo: enough published research to suggest they work, but not enough FDA-quality clinical trial data to satisfy US regulatory requirements

notably, HMOX2 emerged as a candidate MERCs protein (Fig

J Alzheimers Dis 50:859871

Higher magnification inset shows condensed sheets of densely vascularized, preadipocyte-appearing cells with a central nucleus and eosinophilic cytoplasm in regions of prior adipocytes (Ad)

Overall, these attributes make PROTAC a powerful platform to address the medium and long-term limitations of traditional drug discovery