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doi: 10.1001/jamanetworkopen.2024.34136 239 ZhengYFangYLiLWangHZhangSZhuYet al

The potential for small molecules to inhibit these pathways and non-selectively inhibit GHR signaling needs to be considered in small molecule discovery studies

Morandi F, Morandi B, Horenstein AL, Chillemi A, Quarona V, Zaccarello G, et al

ALD encompasses a spectrum of conditions, ranging from simple steatosis to more severe forms such as steatohepatitis, cirrhosis, and fibrosis, ultimately progressing to hepatocellular carcinoma [10]

With the upregulation of AMPK signaling, there is a subsequent increase in the process of burning fatty acids and hence reduction in the generation of energy from fats

Sun L (2013) Peptide-based drug development