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Moreover, chitosan-based nanostructures can enhance multiple aspects of drug performance, including cellular transport and other biological activities (98)

Kawasaki, H

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21,22 The stoichiometric ratio (n) can be determined by isothermal titration calorimetry (ITC), which gives other parameters in addition to the complex ratio named the enthalpy, the entropy, and the binding constant, indicating the complexing affinity of the selected drug to the kind of cyclodextrin cavity