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This makes it a valuable tool for assessing the mechanisms underlying -cell dysfunction in this condition

The authors were able to show increased damage to mitochondrial DNA in both idiopathic PD and in patients carrying the G2019S LRRK2 mutation, and found that mitochondrial DNA damage correlated with LRRK2 kinase activity

[373] claimed that chlorogenic acid is able to reduce DSS-induced colonic mucosal damage, by alleviating DSS-induced inflammation, oxidative stress, and apoptosis in the colon, while reducing ERK1/2, p -ERK, p38, p-p38, JNK, and p-JNK protein expression

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Griffiths and Flatters, 2015)

DOI: Giuliano G (2014) Plant carotenoids: genomics meets multi-gene engineering