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Gene- and proteostasis-based strategies for monogenic disorders For diseases driven by single-transporter defects, gene-based therapies and pharmacological chaperones that restore proper trafficking, stability or function of mutant zinc transporters represent plausible longer-term strategies

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proteins deriving from flagellates, can trigger innate immune responses via TLR5 in the skin of chronically-inflamed mouse models, thus pushing towards tumour formation [62]

2006, Philadelphia: Lippincott, Williams and Wilkins, 537-544

doi: 10.4103/0973-7847