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While both the N-terminal and C-terminal regions of ATG2 exhibit affinity for membranes, studies conducted in cellular contexts suggest that the function of the N-terminal region is linked to its interaction with the ER, whereas the C-terminal amphipathic helix plays a crucial role in directing ATG2A to phagophores and lipid droplets (Tamura et al, 2017

Optic nerve disease research has demonstrated that Semax can support optic nerve function and visual outcomes in conditions including optic nerve atrophy and ischemic optic neuropathy

ZNF423 mutations are associated with Joubert Syndrome, a ciliopathy causing cerebellar vermis hypoplasia and ataxia

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10.1016/j.neubiorev.2011.12.005 Neurosci

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