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Similar to the previous findings, the light-adapted states of the B 12 -bound Ab Pcob and the holo Sas Pcob (i.e., both AdoCbl and BV bound) activate Ab DGC catalysis

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Isatuximab interacts with a discontinuous epitope partially overlapping the catalytic site, whereas Daratumumab binds to two continuous amino acid sequences situated outside the enzymatic active site of CD38 ( i.e

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