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These DNA-damage recognition proteins have been shown to deliver signals from DNA breaks to downstream proteins such as p53, p73 and mitogen-activated protein kinases (MAPK), which activate apoptosis and other forms of cell death [21]

We further used a LEGENDplex kit to quantify asthma-associated cytokine levels

Although astrocytes can utilize fatty acids as an alternative energy source, prolonged reliance on lipid oxidation results in oxidative stress and mitochondrial impairment, exacerbating neurodegeneration 82

doi: 10.3389/fenvs.2014.00053 31 DatJ.VandenabeeleS.VranovE.Van MontaguM.Inz*D.Van BreusegemF

Iron is imported via endocytosis of Fe 3+ -loaded Tf, or via DMT1 for non-transferrin-bound iron (NTBI), and the zinc transporter protein, SLC39A14, and stored in the labile iron pool (LIP) or as ferritin [23]

The same enzymes designed to break down dietary protein into amino acids