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In the presence of excess oxygen methylcobalamin is photolyzed at a rapid rate to yield aquocobalamin and formaldehyde as the major products

doi: 10.1161/JAHA.124.034203 60 FanCLiangWWeiMGouXHanSBaiJ

One key study found altered metabolic activity in the brain that led to a shift toward lactic acidosis during mood episodes (Machado-Vieira et al., 2017b)

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The lack of a glutathione peroxidase gene raises doubts about the relevance of the glutathione (GSH) pathway in detoxification of oxidative stress in Plasmodium