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Parrish AR, Chen G, Burghardt RC, Watanabe T, Morisseau C, Hammock BD

Oxidative stress affects numerous molecular pathways, including inhibition of the cystine/glutamate antiporter system, decreased expression of GPX4, disruption of iron homeostasis and lipid peroxidation, which is a major driver of ferroptosis activation (54)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Yu L., Wan F., Dutta S., Welsh S., Liu Z., Freundt E

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