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Hoffmann K, Czapp M, Lscher W

The recommended dose of pemetrexed for injection for maintenance treatment of non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle until disease progression or unacceptable toxicity after four cycles of platinum-based first-line chemotherapy

Neurochemical shifts via paraxanthine intake Throughout this study, researchers also looked into the impacts of paraxanthine intake on neurotransmitters and other key neurochemicals

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doi: 10.2337/dc10-1006 253 SekharR

Pizzorno, 2014 The skin brightening effects of glutathione driven by its inhibition of tyrosinase and consequent reduction in eumelanin synthesis are well documented and represent a visible clinical marker of the deeper antioxidant restoration it produces systemically