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This observation suggests that excessive GSH concentrations may have a deleterious effect on enzyme activity and protein secretion, indicating an optimal threshold for GSH that supports cellular function without hindering biochemical processes

This progressive cellular damage contributes to accelerated cutaneous aging, manifesting as xerosis, erythema, and premature wrinkle formation

& Baric, R

Coexpression network analysis reveals integrated regulatory mechanisms The further co expression analysis of genes, metabolites, and TFs networks within glutathione, phenylpropanoid, and flavonoid biosynthesis pathways identified a highly interconnected network showing an intertwined regulatory complex

4,6 The present study has demonstrated that citicoline increases glutathione levels after transient forebrain ischemia, which could increase the scavenging of oxygen radicals by GSH

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