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Author contributions GE, PS, GO, GE, FO, OO, SN, OR, MA, MO, RA, WN, PI were responsible for the conception and design of the study

For example, in a 16-week, placebo-controlled trial of an age-advanced cohort receiving nightly subcutaneous GHRH analogue (a sermorelin-like peptide), treatment activated endogenous GH pulsatility and significantly increased integrated nocturnal GH levels