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These enzymes can either detoxify drugs/xenobiotics by converting them into less harmful compounds 0.4-NP is a potent inhibitor to these cytochrome P 450 enzymes CYP1A2, CYP2C19, and CYP2D6 causing toxicity in the body of any organism which is exposed to any kind of xenobiotics or pollutants

Liu Y., Cui D., Hoshii Y., Kawano H., Une Y., Gondo T., Ishihara T

the conversion of homocysteine and methyl-tetrahydrofolate to methionine and tetrahydrofolate by the cytoplasmic methionine synthetase (METR-1 in C

The autoradiographic localization of L-[ 3 H] glutamate in rat brain tissue

Further studies should aim to establish whether these metabolomic changes are causal in AF development and whether dietary interventions to restore metabolomic homeostasis could be a viable therapeutic strategy