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doi: 10.2527/jas1989.67123437x 73 MengutayM.CeylanY.KutmanU

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10.1007/s00213-017-4813-4 38 HirvonenJ.GoodwinR

For instance, CAR-T cell therapy-associated immune effector cell hemophagocytic syndrome is initially managed with corticosteroids as the first-line immunosuppressive treatment

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Structural Differences IGFDES is IGF1 missing the first 3 amino acids (DES(1-3)) IGF1 LR3 is a long-chain version of IGF1 with 13 additional amino acids at the N-terminal These structural modifications change how they interact with IGF binding proteins (IGFBPs) and how long they remain active in the body