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Certain therapies may not be appropriate during pregnancy or breastfeeding

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Furthermore, the CTLA-4 gene placed on 2q33 is known as the second most important immunoregulatory gene in autoimmune thyroid disease

16 It has been shown that influenza viruses induce oxidative stress mediated by an excess of ROS and a decrease of reduced glutathione, and that such conditions favour viral replication, with glutathione depletion pivotal for the folding and maturation of the viral glycoprotein and therefore viral replication

The first and biggest concern is that if EGF is so good at stimulating cell proliferation, how does it relate to cancer