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These effects collectively contribute to a reduction in key renal function indicators, such as serum creatinine (SCr), blood urea nitrogen (BUN), and 24 h urinary protein, by 2041.1% compared to baseline levels, as well as amelioration of renal histopathological alterations, thus effectively preserving renal function and retarding DN progression (7275) (Figure 5)

Protection from MPTP-induced neurotoxicity in differentiating mouse N2a neuroblastoma cells

2019 Mar 18;21(4):486-497

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Endothelial cells co-cultured with neutrophils exposed to high glucose and oleic acid showed increased cytolysis, which could be prevented by an antioxidant, N-acetylcysteine