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In the present study, we show that HPV-16 E7 expression in immortalized human keratinocytes alters the cellular redox equilibrium and induces cell survival by stabilizing a subset of the GSTP1 protein in its reduced monomeric form

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MiRNAs, first found in Caenorhabditis elegans by Lee in 1993 48 , can regulate multiple metabolic pathways in humans at the level of translation and transcription and play a key role in regulating tumor cell growth, migration, invasion, and inducing resistance to chemotherapy 49