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Therefore, the role of STAT3 in c-MET signaling is probably context- and tissue-dependent

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Immune cells, such as macrophages, are recruited to the site of tumor growth, and their activity further increases ROS production, contributing to a positive feedback loop that sustains inflammation and supports melanoma cell survival 71

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TBI treatment includes pharmacotherapy, cognitive therapies and surgeries, which depend on the severity of the condition (Stocchetti et al., 2017)

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