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Older adults may be at higher risk because age-related muscle loss can already be present before treatment begins

Reference Qu, He, Yang, Lin, Yang, Wu, Li and Yang2020

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Role of p66shc in Renal Toxicity of Oleic Acid

doi: 10.1038/srep34538 48 SiristatidisCSergentanisTNVogiatziPKanavidisPChreliasCPapantoniouNet al

Cells were then centrifuged, and the resulting cell pellets were resuspended in DMEM (without phenol red and serum) containing DAF-FM-DA (10 M, for NO detection), DCFH-DA (10 M, for ROS detection) or BODIPY-581/591-C11 (10 M, for lipid-ROS detection)