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Furthermore, oxidative stress is caused by free radicals or oxidant productions, including lipid peroxidation, protein modification, and DNA damage, and results in cellular degeneration and neurodegeneration from damage to macromolecules [36,107]

C (101 MHz, MeOD): 174.49 (C), 172.86 (C), 172.60 (C), 171.54 (C), 171.49 (C), 161.66 (q, J = 36.3 Hz, CF 3 C O), 135.79 (t, J = 24.4 Hz, CH), 134.39 (td, J = 25.0, 9.9 Hz, CH), 131.04 (td, J = 25.2, 12.6 Hz, CH), 119.7o (d, J = 86.2 Hz, C), 53.79 (CH), 53.52 (CH), 43.42 (CH 2 ), 41.83 (CH 2 ), 40.74 (CH 2 ), 40.24 (CH 2 ), 32.37 (CH 2 ), 29.46 (CH 2 ), 28.74 (d, J = 16.8 Hz, CH), 27.03 (CH 2 ), 23.13 (d, = J 4.3 Hz, CH), 22.67 (d, J = 51.3 Hz, CH)

Overall graft dysfunction, defined as EAD in the HOPE-L and DGF in the HOPE-K groups, was 10% vs

Psychiatry 47 , 351354 (2000)

10.3980/j.issn.1672-5123.2024.2.04 17 ChoH

11,78 Moreover, suppressing either component of system Xc induces ferroptosis by disturbing cystine uptake, then limiting GSH synthesis