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Furthermore, in progressive high-fat feeding of mice, phosphorylation was decreased only after the onset of overt muscle insulin resistance [24]

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J Cell Sci 130:938949 Guichard P, Laporte MH, Hamel V (2023) The centriolar tubulin code

Briefly, exclusion criteria were evidence of hemodynamically significant valvular heart disease, surgery, or trauma within the previous month, known cardiomyopathy, known malignant diseases, febrile conditions, or oral anticoagulant therapy within the previous four weeks

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This provides a dual therapeutic benefit for both insulin-sensitive and insulin-resistant women with PCOS (la Marca et al., 1999