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N.BirchmeierW

doi: 10.1523/jneurosci.1409-19.2019

The effects of ROS depend on the dose and persistence of the ROS particles, as well as the type of cells involved

Cytochrome P450 4F2 (CYP4F2) initiates -oxidation of tocochromanols, a process that is followed by -oxidation to carboxyethyl hydroxychromanol (CEHC), which can be conjugated with glucuronide or sulfate and excreted in urine or bile