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FerrDb V2: Update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations

In the process of chronic inflammation, microglia are activated, and then a series of inflammatory mediators are continuously released, leading to oxidative stress response

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The RNA helicase domain primarily participates in the processing and assembly of 18S rRNA, while mutations in the acetyltransferase domain can completely inhibit the acetylation of 18S rRNA and RNA [315, 316]