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Neelakantan H, Vance V, Wetzel MD, Wang H-YL, Mchardy SF, Finnerty CC, Hommel JD, Watowich SJ (2018) Selective and membrane-permeable small molecule inhibitors of nicotinamide N -methyltransferase reverse high fat diet-induced obesity in mice

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Furthermore, when comparing the combination therapy to the standard treatment, Donepezil, the reduction in A plaque burden in both the cortex and hippocampus was similar between the groups, while the combination group showed a trend towards lower levels of soluble A