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In the structure of the GST-glutathione complex, two conserved water molecules are observed, one of which hydrogen bonds directly to the sulphur atom of glutathione and the other forms hydrogen bonds with residues around the glutathione-binding site

However, insulin resistance leads to disturbance in forming this complex, and eventually affects the RB protein in a way that alpha-synuclein (SNCA) protein, which is primarily found in neural tissue, interacts with the formation of amyloid- plaque in the brain

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BMC Clin Pathol 14(1):1 Yi J, Huang WZ, Wen YQ, Yi YC (2019) Effect of miR-101 on proliferation and oxidative stress-induced apoptosis of breast cancer cells via Nrf2 signaling pathway

De novo glycine synthesis is reduced in adults with morbid obesity and increases following bariatric surgery

PubMed , Seminars in Immunopathology , vol