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Combined treatment with CDK4/6 and IGF-IR inhibitors synergistically inhibits Ewing sarcoma [132]

After nuclear labelling, cells were washed with 1xPBS, and the plates were stored with 100 l of PBS/well, protected from light at 4 C or taken directly to the Operetta automatic cell imaging system (PerkinElmer, MA, USA)

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(1998) Eur

doi: 10.1017/S000711451900148X 90

AMPK Activation as the Core Mechanism Berberine activates AMP-activated protein kinase (AMPK) in hepatocytes and skeletal muscle, a pathway that overlaps meaningfully with metformin [5]