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Arendt JFH, Pedersen L, Nexo E, Srensen HT

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Mechanistic Studies Subsequent research has explored the mechanisms by which NNMT regulates metabolism, with studies demonstrating that NNMT activity reduces cellular NAD+ availability, affects SAM-dependent methylation reactions, modulates sirtuin activity, and influences adipocyte differentiation and function

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therefore, understanding nanoparticle behavior and nanoparticle-endothelial cell interactions under flow conditions following intravenous administration is essential ( in vivo (Qin et al., 2022)