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Redox reactions initiated by therapy induce significant changes in cells, pathways regulating survival, and inflammation, as well as induce an up-regulation of antioxidant enzymes, thereby promoting conformational changes in the drug transporters

Figure 1 Redox Dysregulation Oxidative stress results from elevated intracellular levels of ROS, and nitrosative stress results from increased levels of RNS, and both events can significantly damage cells

Bioresour Technol 258:302309

This is because glutathione deficiency contributes to oxidative stress, which plays a key role in these and other disease pathogenesis such as seizures, Alzheimers disease, liver disease, sickle cell anemia, cancer, heart attack, stroke, and diabetes

62 In its first three months, approximately 800 people used the center more than 9500 times and it averted at least 150 overdoses

Its nutritional profile and the richness and diversity of bioactive compounds highlight the role of faba beans in maintaining human health and disease prevention 2,12