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Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by activating NF-kappa B via Ref-1

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Plasma vitamin E was increased in the GSTM1-null group, while glutathione levels were increased in the GSTM1-present group, and blood vitamin C levels were increased in the GSTT1-present genotype, demonstrating the antioxidant impact of the grape juice differed based on the genotype of the participants

doi:10.1089/ARS.2009.2695 Morris D, Khurasany M, Nguyen T, et al

26 HakmaouiA.Prez-BuenoM

AG-221, a small molecule mutant IDH2 inhibitor, remodels epigenetic state of IDH2-mutant cells and induces alterations in self-renewal/differentiation in IDH2-mutant AML model in vivo