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Reduced inflammatory cytokine activity, improved microvascular integrity, and beneficial effects on pain modulation through peripheral and dopaminergic mechanisms are among the reported effects in animal studies

In some instances, due to conditions such as pernicious anaemia, the body may struggle to absorb enough B12 from diet alone, necessitating supplementation

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Finally, aging itself can reduce the ability of the stomach to produce IF

The letter, along with the list of effected peptides, is available here

A low mood that doesn't lift despite doing "all the right things." You start searching for answers, and somewhere between the medical websites and the social media posts, you land on B12 deficiency as a possible explanation