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Glutathione synthesis Glutathione, is synthesized from 3 amino acids (Glu, Cys, Gly), and its reduced form GSH protects cells from oxidative damage during normal cell processes and contributes to the processing of certain xenobiotics including toxins and drugs

Cisplatin was administered intravenously at a dose of 75 mg/m 2 approximately 30 minutes after pemetrexed administration on Day 1 of each cycle, gemcitabine was administered at a dose of 1,250 mg/m 2 on Day 1 and Day 8, and cisplatin was administered intravenously at a dose of 75 mg/m 2 approximately 30 minutes after administration of gemcitabine, on Day 1 of each 21-day cycle

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KL collected the references