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Acknowledgements This work was supported by the National Natural Science Foundation of China (grant no 81500354), Beijing Municipal Natural Science Foundation (grant no Z13110200400000) and Wu Jieping Medical Foundation (grant no 320.6750.14331)

Inhibiting the activity of NADPH oxidase significantly abrogated EC senescence 10

Moreover, ferroptosis serves a crucial role in the occurrence and development of gliomas, as well as the metabolic process of anxiety and depression, which can be caused by cancer

The young leaves are particularly important in pharmacological research, as their components are more potent than those found in mature leaves (218, 219)

IHC staining of human kidney using 55463-1-AP Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 55463-1-AP (Phospholipase C epsilon 1 antibody) at dilution of 1:1000 (under 10x lens)