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This is then converted to S-adenosylmethionine (SAM), the universal methyl donor

It is essential that clinical trials can be developed to effectively compare these routes of administration and that clinicians can share their experiences with these modalities of B12 administration so that they can be popularised and considered as viable alternatives for patients

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In life-threatening cases, 5,000,000mcg of B12 is given directly to the veins within a 15 minute window

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