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Schlag BD, Vondrasek JR, Munir M, Kalandadze A, Zelenaia OA, Rothstein JD, et al

This oncometabolite impairs cytotoxic T-cells function while CRC cells preference for glycolysis over OXPHOS further reinforces immune evasion mechanisms, critically shaping therapeutic responses to immunotherapy

doi: 10.1016/j.febslet.2004.10.043 266 Martinez-ZaguilanRSeftorEASeftorREChuYWGilliesRJHendrixMJ

Storage:Store in a dry, cool place (at room temperature) in tightly closed original packaging

Khan A, Khan I, Halim SA, Rehman NU, Karim N, Ahmad W, Khan M, Csuk R, Al-Harrasi A

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells, and deletion of DNMT1 and DNMT3b eliminates methyltransferase activity and reduces genomic DNA methylation (global DNA hypomethylation) by greater than 95% (76)