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5), showing a similar effect to Bay11-7082, which indicated that DIS attenuated the inflammatory response by suppressing the NF-B pathway

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155 Crosstalk of NF-B signaling with Notch signaling The Notch signaling consists of Notch receptors, Notch ligands, CBF-1/Suppressor of hairless/Lag (CSL)-DNA-binding proteins, intracellular effector molecules, and regulators of Notch, which regulate diverse cellular processes including proliferation, stem cell maintenance, differentiation, and death

wound healing pathways