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Saadeldin, I

ISfinder: the reference centre for bacterial insertion sequences

For example, the quantitative contribution of the lactate shuttle likely varies by brain region and neural activity, and the interplay between its roles as an energy substrate and a signaling molecule (e.g., in epigenetic regulation) is poorly defined

These substances are highly reactive and capable of causing damage to key cellular components and organelles, including lipids, nucleic acids, and proteins, leading to the onset of senescence [53, 54]

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This narrow focus limits pro-angiogenic therapeutics as peptides, similar to proteins, suffer from poor pharmacokinetics in vivo , necessitating the development of controlled release systems