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Lethal fraction scores were calculated at each time point as previously described, with two modifications (Forcina et al, 2017): (i) because long-dead cells can release SG, the maximum number of SG positive counts from the start of the time course was used in these calculations

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This technology is one example of a method of decreasing levels of a polypeptide, preferably a secreted form, due to a variety of etiologies, such as cancer

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