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Trewavas, and M.R

24:153-159 [PMC free article: PMC3645348] [PubMed: 23241513] 24

doi: 10.1074/jbc.M809338200

The practical approach is to use a lower concentration (5mg/mL) for the first 8-12 weeks when precision matters most during introduction, then switch to a higher concentration (10-20mg/mL) as you move into higher doses

This underscores the need for a more nuanced therapeutic approach, balancing the reduction of copper toxicity with the preservation of physiological functions, and highlights the importance of reliable biomarkers to monitor copper levels during treatment