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Each sample was tested in triplicate, and the transfections were repeated, with the number of replicates detailed in the figure legends

For patients with PD-L1- a/m TNBC disease, upcoming phase III trials to determine the optimal first-line therapy include the ASCENT-03 (NCT05382299) trial, which is investigating SG compared to treatment of physicians choice and TROPION-Breast 02 (NCT05374512), which investigates Dato-DXd against treatment of physicians choice

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Cold Spring HarbPerspect Med 2(2):a009399 Stratman NC, Carter DB, Sethy VH (1997) Ibuprofen: effect on inducible nitric oxide synthase

Additionally, both AMPK and ULK1 can phosphorylate Atg9, a transmembrane protein involved in the early formation of autophagosomes, thereby exerting control over its localization