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Description

(2023a) identified a natural NQO1 substrate, 2-methoxy-6-acetyl-7-methyljuglone (MAM), which has potent anti-cancer effects

Heterogeneity within GBM (regional genetic variance and cellular hierarchies often regulated by different CSC niches) is accepted as the basis for resistance to multiple treatments (155, 156)

Diclofenac has known human metabolites that include (2S,3S,4S,5R)-6-[2-[2-(2,6-Dichloroanilino)phenyl]acetyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid, 4'-hydroxydiclofenac, and 5-hydroxydiclofenac