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There is some evidence for the association between maternal ID and preterm delivery [16], low birth weight [17], possible placental abruption, and increased peripartum blood loss [18]

Its combined role in heart-brain coexisting diseases suggests that inhibiting CD38 has a protective effect on cardiovascular diseases (CVD) and neurological disorders

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Known as ascorbic acid, is necessary for the growth, development and repair of all body tissues

Additionally, other researchers have observed deposition of type I collagen in the smooth muscle cells of coronary arteries of CD38 KO mice, but found that CD38 deficiency did not affect the expression of type I collagen protein and mRNA, indicating that CD38 regulates the degradation of type I collagen by inhibiting autophagosome and lysosomal fusion [34]

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