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Dec 2004;2(12):2138-45

Oxford: Oxford University Press, 2010

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Out of five different carrier lipids tested (including MCT, coconut, olive, and soybean oils, and cocoa butter), it was observed that -caryophyllene-loaded lipid nanocarriers using MCT oil exhibited the most robust freezethaw stability while also undergoing the fastest lipid degradation during simulated in vitro digestion

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This depletion significantly promoted liver inflammation and hepatic lipid accumulation in vitro, along with an upregulation of lipogenic gene pathways such as SREBP-1/FASN