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Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm

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The structure comprises the typical GST fold with an N-terminal thioredoxin-like domain ( 1 1 2 2 3 4 3 ) and an all-helical C-terminal domain ( 4 5 6 7 8 )

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This may in particular be beneficial for patients with low or insufficient SSTR expression

Heat stress and oxidative damage can compromise epithelial integrity, increase permeability, and lead to immune dysfunction (200, 201)