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Description

As it was previously demonstrated that lysine lactylation was induced by neural excitation, a key molecular mechanism for the development of epilepsy [96], with the detailed results showing the positive association of increase of lysine lactylation and the expression of the immediate-early gene marker of neuronal activity c-Fos [97], it is hypothesized that histone delactylation by HDAC1-3 may inhibit the development of epilepsy and prevent seizures

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6(6): 9 German Ministry of Health, German Institute for Drugs and Medical Devices (BrArM), Federal Dental Chamber, Kassenzahnrztliche Bundesvereinigung, German Scientific Dental Association, German Association for Operative Dentistry, et al

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