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We will examine how complex chronic conditions like Long COVID and ME/CFS disrupt these vital metabolic pathways, leading to severe fatigue and cardiovascular strain

In addition, the second-generation PI carfilzomib and the only oral drug ixazomib have been approved, and if they can demonstrate the same antitumor efficacy as BTZ, then PN may become a minor issue in the treatment of MM, resulting in an improved quality of life for the patient and a reduced financial burden (Perrot et al., 2024