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References Stefano GB, Ptacek R, Ptackova H, Martin A, Kream RM

Adverse effects of acetylcysteine following oral inhalation or intratracheal instillation may include stomatitis, nausea, vomiting, drowsiness, clamminess, severe rhinorrhea, and fever

Models available at References Liu, J., Ning, W., Zhang, N., Zhu, B

Yes this is one of its advantages over oral supplementation

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