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As with other calcium channel blockers, hemodynamic measurements of cardiac function at rest and during exercise (or pacing) in patients with normal ventricular function treated with amlodipine have generally demonstrated a small increase in cardiac index without significant influence on dP/dt or on left ventricular end diastolic pressure or volume

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Neurodevelopmental disorders and cancer To that point, the researchers also identified glutathione-linked molecular mechanisms that may contribute to very different diseases

Long-term safety studies, however, have not been conducted (see Concerns and Cautions)