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Pharmaceutical development of Nrf2 modulators The identification of Nrf2 as a master regulator of cellular antioxidant defenses has revolutionized our understanding of its pivotal role as a therapeutic target in the pathogenesis of inflammatory diseases

Note: If you are pregnant or breastfeeding, please consult your doctor before starting a new skin care regimen

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Potential considerations include: Mild Skin Irritation As with many skincare ingredients, some individuals may experience: Temporary redness Mild irritation Sensitivity Dryness Patch testing is often recommended before regular use

These data revealed that cytotoxic chemotherapeutic agents with different mechanisms of action, including taxanes and platinum-containing compounds, can trigger senescence of normal and malignant cells in different tissues in vivo that may worsen prognosis of the disease